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Visualization of amino acid composition differences between processed protein from different animal species

Xingfan ZHOU,Zengling YANG,Longjian CHEN,Lujia HAN

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 2,   Pages 171-179 doi: 10.15302/J-FASE-2016095

Abstract: Amino acids are the dominant organic components of processed animal proteins, however there has been

Keywords： self-organizing feature maps     visualization     processed animal proteins (PAPs)     amino acid    

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ANTIVIRAL EFFECTS OF BACTERIOCIN AGAINST ANIMAL-TO-HUMAN TRANSMITTABLE MUTATED SARS-COV-2: A SYSTEMATIC

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 4,   Pages 603-622 doi: 10.15302/J-FASE -2021397

Abstract:

The COVID-19 infections caused by SARS-CoV-2 have resulted in millions of people being infected and thousands of deaths globally since November 2019. To date, no unique therapeutic agent has been developed to slow the progression of this pandemic. Despite possessing antiviral traits the potential of bacteriocins to combat SARS-CoV-2 infection has not been fully investigated. This review summarizes the mechanisms by which bacteriocins can be manipulated and implemented as effective virus entry blockers with infection suppression potential properties to highly transmissible viruses through comprehensive immune modulations that are potentially effective against COVID-19. These antimicrobial peptides have been suggested as effective antiviral therapeutics and therapeutic supplements to prevent rapid virus transmission. This review also provides a new insight into the cellular and molecular alterations which have made SARS-CoV-2 self-modified with diversified infection patterns. In addition, the possible applications of antimicrobial peptides through both natural and induced mechanisms in infection prevention perspectives on changeable virulence cases are comprehensively analyzed. Specific attention is given to the antiviral mechanisms of the molecules along with their integrative use with synthetic biology and nanosensor technology for rapid detection. Novel bacteriocin based therapeutics with cutting-edge technologies might be potential substitutes for existing time-consuming and expensive approaches to fight this newly emerged global threat.

 

Keywords： antimicrobial proteins / antiviral profiling of bacteriocins / antiviral therapeutics / immunomodulation    

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Novel engineered proteins for mechanomaterials

Giuseppe Portale

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 6,   Pages 1122-1123 doi: 10.1007/s11705-020-1941-x

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Paradoxical role of Id proteins in regulating tumorigenic potential of lymphoid cells

Sumedha Roy, Yuan Zhuang

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 374-386 doi: 10.1007/s11684-018-0652-x

Abstract:

A family of transcription factors known as Id proteins, or inhibitor of DNA binding and differentiationDue to their ability to promote self-renewal, Id proteins have been considered as oncogenes, and potentialwith respect to inhibition of their canonical DNA binding partners known as E proteins.Transcriptional regulation by E proteins, and their antagonism by Id proteins, act as gatekeepers toThese mechanistic insights can allow better appreciation of the context-dependent roles of Id proteins

Keywords： Id proteins     lymphoma     leukemia     T cells     B cells     tumor suppressor     oncogene    

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Comparative genotoxicity of water processed by three drinking water treatment plants with different water

Ting Zhang, Heze Liu, Yiyuan Zhang, Wenjun Sun, Xiuwei Ao

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 3, doi: 10.1007/s11783-020-1214-4

Abstract: Genotoxicity of substances is unknown in the water after treatment processes. Genotoxicity decreased by activated carbon treatment but increased by chlorination. Halogenated hydrocarbons and aromatic compounds contribute to genotoxicity. Genotoxicity was assessed by umu test; acute and chronic toxicity by ECOSAR. Inconsistent results confirmed that genotoxicity cannot be assessed by ECOSAR. Advanced water treatment is commonly used to remove micropollutants such as pesticides, endocrine disrupting chemicals, and disinfection byproducts in modern drinking water treatment plants. However, little attention has been paid to the changes in the genotoxicity of substances remaining in the water following the different water treatment processes. In this study, samples were collected from three drinking water treatment plants with different treatment processes. The treated water from each process was analyzed and compared for genotoxicity and the formation of organic compounds. The genotoxicity was evaluated by an umu test, and the acute and chronic toxicity was analyzed through Ecological Structure- Activity Relationship (ECOSAR). The results of the umu test indicated that biological activated carbon reduced the genotoxicity by 38%, 77%, and 46% in the three drinking water treatment plants, respectively, while chlorination increased the genotoxicity. Gas chromatograph-mass spectrometry analysis revealed that halogenated hydrocarbons and aromatic compounds were major contributors to genotoxicity. The results of ECOSAR were not consistent with those of the umu test. Therefore, we conclude that genotoxicity cannot be determined using ECOSAR .

Keywords： Drinking water     Treatment process     Genotoxicity     Umu test     Ecological Structure-Activity Relationship    

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Highlights for special issue on “Large Animal Stem Cells”

Jianyong HAN

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1,   Pages 1-2 doi: 10.15302/J-FASE-2019251

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A brief review of genome editing technology for generating animal models

Haoyi WANG, Sen WU, Mario R. CAPECCHI, Rudolf JAENISCH

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2,   Pages 123-128 doi: 10.15302/J-FASE-2019309

Abstract: power to alter DNA sequences at chosen genomic loci, thereby generating various genetically edited animalthe development of major genome editing tools, focusing on the application of these tools to generate animal

Keywords： animal model     CRISPR     genome editing     TALEN     ZFN    

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Cryopreservation of farm animal gametes and embryos: recent updates and progress

Zhengyuan HUANG, Lei GAO, Yunpeng HOU, Shien ZHU, Xiangwei FU

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1,   Pages 42-53 doi: 10.15302/J-FASE-2018231

Abstract:

Cryopreservation has undergone tremendous advances and is widely used in animal production based on

Keywords： vitrification     gametes     embryo     animal production     cryoprotective agent     freezability    

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Caveolin proteins: a molecular insight into disease

Hongli Yin,Tianyi Liu,Ying Zhang,Baofeng Yang

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 397-404 doi: 10.1007/s11684-016-0483-6

Abstract: This article focuses on the relationship between caveolin proteins and human diseases and reviews the

Keywords： caveolin     caveolae     microRNA     disease     signaling pathway     heart     tumor    

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The speciation, leachability and bioaccessibility of Cu and Zn in animal manure-derived biochar: effect

Qi Lin, Xin Xu, Lihua, Wang, Qian Chen, Jing Fang, Xiaodong Shen, Liping Lou, Guangming Tian

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 3, doi: 10.1007/s11783-017-0924-8

Abstract: Biochars derived from animal manures may accumulate potentially toxic metals and cause a potential risk

Keywords： Animal manure     Biochar     Metals     Molecular species     Pyrolysis    

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Highlights of special issue on Animal Science

Jun REN

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3,   Pages 257-259 doi: 10.15302/J-FASE-2017165

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Antimicrobial use in food animal production: situation analysis and contributing factors

Ziping WU

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 3,   Pages 301-311 doi: 10.15302/J-FASE-2018207

Abstract: antimicrobial use at farm level, this study discusses the main knowledge gaps in antimicrobial use in food animalFactors associated with animal health (including antimicrobial resistance), animal health improvement, economic costs and benefits relevant to animal diseases, and potential technological alternatives or

Keywords： antimicrobial use     drivers for antimicrobial use     food animal production    

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Electrolyzed water and its application in animal houses

Weichao ZHENG,Li NI,Baoming LI

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 3,   Pages 195-205 doi: 10.15302/J-FASE-2016109

Abstract: its production, there is reduced corrosion of surfaces and it minimizes the potential for damage to animallast decade, EW has become increasingly popular as an alternative disinfectant for decontamination in animalantimicrobial mecha- nism of EW, and recent developments related to the application of SAEW and NEW in animal

Keywords： disinfection     poultry and livestock     slightly acidic electrolyzed water     neutral electrolyzed water    

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Changes in structure and functional properties of whey proteins induced by high hydrostatic pressure:

Xiaoming LIU, Jia NING, Stephanie CLARK,

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 4,   Pages 436-442 doi: 10.1007/s11705-009-0251-0

Abstract: the research conducted to understand the effect of HHP on structure and functional properties of whey proteins

Keywords： -lactoglobulin     processing     functional     alternative technology     environmental    

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Cross-sectional network analysis of plasma proteins/metabolites correlated with pathogenesis and therapeutic

Frontiers of Medicine doi: 10.1007/s11684-023-1022-x

Abstract: heightened proliferation and energy consumption in APL blasts, and the other featured APL plasma-enriched proteinsfrom therapy-induced cell death or senescence and ensuing supraphysiological levels of intracellular proteins

Keywords： acute promyelocytic leukemia     plasma proteomics     plasma metabolomics     cross-sectional correlation network     pathogenesis     treatment    

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Title Author Date Type Operation

Visualization of amino acid composition differences between processed protein from different animal species

Xingfan ZHOU,Zengling YANG,Longjian CHEN,Lujia HAN

Journal Article

ANTIVIRAL EFFECTS OF BACTERIOCIN AGAINST ANIMAL-TO-HUMAN TRANSMITTABLE MUTATED SARS-COV-2: A SYSTEMATIC

Journal Article

Novel engineered proteins for mechanomaterials

Giuseppe Portale

Journal Article

Paradoxical role of Id proteins in regulating tumorigenic potential of lymphoid cells

Sumedha Roy, Yuan Zhuang

Journal Article

Comparative genotoxicity of water processed by three drinking water treatment plants with different water

Ting Zhang, Heze Liu, Yiyuan Zhang, Wenjun Sun, Xiuwei Ao

Journal Article

Highlights for special issue on “Large Animal Stem Cells”

Jianyong HAN

Journal Article

A brief review of genome editing technology for generating animal models

Haoyi WANG, Sen WU, Mario R. CAPECCHI, Rudolf JAENISCH

Journal Article

Cryopreservation of farm animal gametes and embryos: recent updates and progress

Zhengyuan HUANG, Lei GAO, Yunpeng HOU, Shien ZHU, Xiangwei FU

Journal Article

Caveolin proteins: a molecular insight into disease

Hongli Yin,Tianyi Liu,Ying Zhang,Baofeng Yang

Journal Article

The speciation, leachability and bioaccessibility of Cu and Zn in animal manure-derived biochar: effect

Qi Lin, Xin Xu, Lihua, Wang, Qian Chen, Jing Fang, Xiaodong Shen, Liping Lou, Guangming Tian

Journal Article

Highlights of special issue on Animal Science

Jun REN

Journal Article

Antimicrobial use in food animal production: situation analysis and contributing factors

Ziping WU

Journal Article

Electrolyzed water and its application in animal houses

Weichao ZHENG,Li NI,Baoming LI

Journal Article

Changes in structure and functional properties of whey proteins induced by high hydrostatic pressure:

Xiaoming LIU, Jia NING, Stephanie CLARK,

Journal Article

Cross-sectional network analysis of plasma proteins/metabolites correlated with pathogenesis and therapeutic

Journal Article